During the month of Ramadan, lifestyle patterns, including eating, sleeping, and physical movement, undergo significant changes that directly affect the body's physiological balance. While some individuals choose to stop exercising due to concerns over fatigue or dehydration, others are determined to maintain their regular training routines. This dichotomy raises an essential question: what does science say about physical activity during fasting? Moreover, do recommendations differ between healthy individuals and those with chronic conditions taking medication? The article explains that, physiologically, the body goes through gradual metabolic phases during fasting. After several hours of abstaining from food, blood glucose levels drop, and the body initially relies on glycogen stored in the liver and muscles, gradually transitioning to using fats as an energy source. These transformations are natural, but they coincide with a gradual decrease in fluids, which can limit physical endurance, especially in hot environments. Scientific reviews published in databases such as PubMed indicate that fasting does not necessarily lead to a comprehensive decline in physical performance, particularly during moderate-intensity exercises. However, it is crucial for those choosing to exercise while fasting to be aware of their hydration levels and the timing of their workouts to avoid potential health risks.