Darío Lopérfido, a notable figure in Argentine culture and politics, passed away on Tuesday, February 27, at the age of 61. He held significant positions such as the Secretary of Culture and Media during Fernando de la Rúa's presidency and was also the Buenos Aires Minister of Culture, among other roles. Lopérfido was instrumental in promoting various cultural festivals, including the Buenos Aires International Festival of Independent Cinema (BAFICI), contributing greatly to the Argentine cultural landscape.

Lopérfido was diagnosed with Amyotrophic Lateral Sclerosis (ALS) in July 2024, an incurable neurodegenerative disease that gradually paralyzes motor neurons and leads to muscle control loss. His condition, which is progressive and debilitating, significantly affected his life in the years leading up to his passing. Challenges posed by ALS often include severe physical limitations, and his diagnosis highlighted the struggle many face with such diseases.

His death marks a significant loss for the Argentine cultural community, where his contributions were felt across multiple eras and administrations. With a career spanning various influential positions, Lopérfido's legacy will likely be remembered for his dedication to the arts and culture in Argentina, and his passing may prompt discussions around support for those suffering from terminal illnesses like ALS, as well as acknowledgment of the cultural impact such figures have on society.