Feb 19 β€’ 17:58 UTC πŸ‡ΈπŸ‡ͺ Sweden Aftonbladet

Obesity medication against alcoholism? New study offers hope

A new study suggests that obesity medications like Mounjaro may effectively reduce alcohol consumption and relapse behaviors in rats and mice.

Recent research from the University of Gothenburg indicates that the obesity medication Mounjaro, which contains tirzepatide, shows promise in combating alcohol dependency. The study observes that tirzepatide not only diminishes alcohol intake but also decreases behaviors associated with relapse in animal models. This adds to previous findings regarding semaglutide, a component of other weight loss and diabetes drugs, which has also been shown to lower alcohol consumption in humans.

Professor Elisabet Jerlhag, who leads the study, highlights the unique mechanism of tirzepatide, which affects two different signaling systems in the brain. This dual action may lead to a stronger effect on reducing alcohol use while potentially minimizing side effects. The connection between alcohol consumption and dopamine modulation, a key neurotransmitter linked with pleasure and reward, plays a critical role in this research, suggesting that medications designed for obesity management could provide an innovative route for treating alcohol use disorders.

As public health officials seek new strategies to address alcohol dependency, findings from this study could pave the way for further clinical studies and potential applications in human medicine. The implications extend beyond simply treating obesity; they may redefine how we approach substance use disorders, aligning weight management strategies with addiction treatment, thus offering new hope to those struggling with alcoholism.

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