The Liberal Party has launched its campaign for the Nepean by-election, appointing Anthony Marsh, the Mayor of Mornington Peninsula Shire, as their candidate following the retirement of former MP Sam Groth. The by-election is set for May 2, with the Liberals reportedly confident in their chances despite the presence of One Nation, which has emerged as a key contender, especially with the Labor Party opting not to field a candidate in this race.

Jess Wilson, the leader of the Victorian Liberals, expressed little concern regarding One Nation's challenge, indicating her belief in the Liberal Party's appeal to voters in the district. Anthony Marsh, although a new addition to the party, has been vocal about his commitment to local governance and unity within the Liberal Party, despite previous declarations that he would not transition from local to state politics. His stance may indicate a shift in the political landscape and reflects the Liberals' strategy to strengthen their foothold in the region amidst the competition.

The election will take place under somewhat unique circumstances, given the lack of a Labor candidate, which typically influences the dynamics of electoral contests. Analysts suggest that this by-election could serve as a referendum on the One Nation party's influence in regional Australia, as well as the effectiveness of the Liberal Party’s local governance approach, particularly with new candidates who come with prior public commitments. The outcome could have significant implications for the party's strategies heading into future elections, especially with regard to how they address local and regional issues over the coming years.