The article explores the significance of International Rare Disease Day on February 28, specifically in the context of South Africa, where over three million people are collectively affected by various rare diseases. Despite the rarity of individual diseases, their overall impact on morbidity and healthcare resources is substantial, underscoring the necessity for greater public and health sector awareness. The narrative centers around the experience of individuals like Mpho Matseka, who suffered for years before finally receiving a correct diagnosis, highlighting the challenges in the healthcare system regarding rare disorders.

Mpho Matseka's journey illustrates the often lengthy and convoluted path many face in obtaining a diagnosis for rare diseases. Initially perceived as mischievous due to his frequent ailments, it took numerous doctors and a stroke of luck for Matseka to receive a definitive diagnosis of Ehler-Danlos Syndrome. His case exemplifies a broader systemic issue; many rare disease patients often endure misdiagnosis or delayed treatment due to lack of knowledge within the healthcare community about these conditions.

The article concludes by calling on both the healthcare system and society to take rare diseases more seriously, advocating for increased funding, improved diagnostic resources, and public awareness campaigns. As International Rare Disease Day aims to shed light on these conditions, it serves as a reminder of the need for a more robust response to the healthcare needs of individuals with rare diseases in South Africa, ensuring that more people receive timely and effective care.