The assassination of Nemesio Oseguera Cervantes, also known as El Mencho, the leader of Mexico's most dangerous drug cartel, has instigated chaos and a series of violent retaliatory acts by his followers. Following a military operation that led to his death on February 22, 2026, violence erupted across twelve states in Mexico, affecting various cities and beach resorts. Armed groups associated with his cartel responded by attacking businesses, igniting banks, and blocking major highways, which has raised concerns about public safety across the nation.

While the Mexican government is labeling this military operation a 'historical success', experts warn that the death of such a notorious figure may ignite further bloodshed rather than stabilize the country. El Mencho was not merely a drug lord; he was the mastermind behind the rise of the Jalisco New Generation Cartel, which has evolved into the most powerful criminal organization in Mexico's history. Unlike previous regional cartels, El Mencho's organization permeated all levels of the state and economy, exerting control over strategic ports, operating avocado farms, and even managing gold mines, which has raised fears about a power vacuum leading to intensified cartel wars.

The implications of El Mencho’s assassination extend beyond mere leadership changes within the cartel. Experts speculate that rivals could engage in more violent power struggles, potentially plunging Mexico into a new era of drug-related violence. As the country grapples with these developments, questions loom concerning how the government will respond and whether it can effectively manage the chaos resulting from the collapse of this cartel empire that spans from East Asia to Australia.