The assassination of Nemesio Oseguera Serrantés, known as 'El Mencho', one of the most powerful drug lords in the world, raises critical questions about the future of his cartel and others in Mexico. His enmity with rival cartels has not only reshaped the landscape of the drug trade but has also triggered a surge in violence across several Mexican states, including Jalisco. The piece explores whether his death signifies the end of the Jalisco New Generation Cartel or if another leader will rise to continue its operations.

As the Jalisco cartel was founded between 2009 and 2010 from remnants of the Milenio Cartel, it quickly became one of Mexico's dominant criminal organizations involved in extensive drug trafficking. The article emphasizes the group's transformation from a minor player into a powerful entity in the narcotics market, and the violent confrontations it has faced, particularly against rivals like the Sinaloa Cartel.

The narrative also delves into the broader implications of cartel leadership deaths and shifts in power dynamics within the Mexican drug trade. With El Mencho's legacy and notorious reputation, the questions surrounding who will fill his void highlight the ongoing struggle and instability that characterize the fight against organized crime in Mexico, casting shadows over the country's security landscape.