Feb 24 • 03:01 UTC 🇧🇷 Brazil G1 (PT)

New feline cancer genome could benefit humans

A new study suggests that genetic mutations causing cancer in cats could provide insights for human cancer treatments.

Recent research published in the journal Science indicates that cats and humans share similar types of cancer influenced by genetic mutations. By analyzing samples from nearly 500 domestic cats without pedigree, researchers have developed what they refer to as the 'feline oncogenome', identifying genetic mutations that are linked to malignant tumors in both species. This genetic research was conducted using a genetically diverse set of samples collected from cats in Canada, the UK, Germany, Austria, and New Zealand.

The study highlights the presence of thirteen different types of cancer in cats, as researchers meticulously examined existing knowledge of one thousand genes known to cause malignant tumors in humans. Notably, they found that half of the tumor samples from the cats showed mutations in the FBXW7 gene, which is associated with tumor development in human cancers. This finding underscores the potential for cross-species insights when it comes to understanding and treating cancer.

The implications of this research are significant, as they may pave the way for new cancer treatments that could be beneficial for both pets and humans. With common genetic traits linking the two species, veterinary and human medical fields could collaborate more closely in developing effective treatment options. This study not only deepens the understanding of feline cancer but also opens avenues for advancements in human oncology, signaling a progressive step in comparative medicine strategies.

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