Feb 23 • 12:01 UTC 🇦🇷 Argentina Clarin (ES)

Extreme Longevity May Have an Unexpected Origin: Genes Inherited from Prehistoric Ancestors

A study indicates that extreme longevity in some individuals may be linked to genetic traits inherited from prehistoric ancestors like Neanderthals and Denisovans.

A recent study conducted by the University of Bologna reveals that the extraordinary longevity observed in certain individuals, particularly those who live beyond 100 years in good health, might be attributed to genetic factors inherited from prehistoric ancestors. The research analyzed the genomes of 333 Italian centenarians, comparing them with younger adults to discern the influence of Western Hunter-Gatherer (WHG) ancestry on extreme longevity. This significant finding reshapes our understanding of human genetics and longevity by suggesting that some longevity-related genes trace back to ancient populations that inhabited Eurasia tens of thousands of years ago.

The implications of this study are profound, as it challenges the conventional narrative that longevity is a modern phenomenon influenced solely by advancements in healthcare and lifestyle. Instead, it highlights the potential genetic legacy left by our prehistoric ancestors who thrived in incredibly harsh environments characterized by cold climates, food scarcity, and high disease exposure. Such survival traits could have been selected over generations, culminating in genetic attributes that contribute to longevity in contemporary populations.

As researchers continue to explore the genetic basis of longevity, this study lays the groundwork for a deeper understanding of human evolutionary history and its effects on health and lifespan today. The work adds a crucial perspective to the ongoing dialogue about aging, genetics, and the interplay between our biological heritage and modern living conditions, suggesting that our past could be more relevant to our present health than previously thought.

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