Feb 11 • 05:00 UTC 🇧🇷 Brazil G1 (PT)

Statins: Cholesterol Reducer is Safer Than the Label Claims

A new meta-analysis finds that statins, widely used to lower cholesterol, may pose fewer side effects than previously indicated in their patient information leaflets.

A recent meta-analysis published in The Lancet by the Cholesterol Treatment Trialists (CTT) Collaboration analyzed the side effects of statins, commonly prescribed medications for reducing cholesterol levels. Statins work primarily by lowering levels of LDL, often referred to as 'bad' cholesterol, which can accumulate in blood vessel walls and increase the risk of heart attacks and strokes. The study findings suggest that statins are not only effective in lowering cholesterol but also in reducing the incidence of heart attacks, strokes, and mortality from cardiovascular diseases.

Throughout the last thirty years, hundreds of millions of people have used statins worldwide, and they have become a cornerstone in preventing cardiovascular events. The consensus among scientists is that the beneficial effects of statins significantly outweigh their side effects. The new findings challenge the biases often associated with the dosing information and possible adverse effects listed on medication leaflets, suggesting that many patients may be unnecessarily hesitant about using statins based on misperceptions about their safety.

Implications of this study are vital, especially for healthcare providers and patients alike. They underscore the importance of clear communication regarding medication benefits and risks. The research may lead to reassessing how statins are presented to patients, potentially resulting in improved adherence to cholesterol management protocols and, ultimately, better cardiovascular health outcomes for many individuals, particularly those at higher risk.

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