Feb 9 • 08:03 UTC 🇧🇷 Brazil G1 (PT)

'Yo-yo effect' reduces brown fat activity and harms metabolism, says Unicamp

A study from Unicamp reveals that the 'yo-yo effect' of repeated weight loss and gain diminishes brown fat activity, negatively impacting metabolism.

A recent study conducted by researchers at Unicamp has shed light on the effects of the 'yo-yo effect,' a term referring to the repeated cycles of weight loss and gain, on brown fat activity and overall metabolism. According to the findings published in the American scientific journal Nutrition Research, this phenomenon not only reduces the effectiveness of brown fat but also leads to detrimental changes in metabolic processes within the body. This research stems from a comprehensive four-year study involving 121 women aged between 20 and 41, who exhibited a variety of body types.

Brown fat, known for its role in burning glucose and lipids to generate heat, serves as an important player in energy expenditure and metabolic health. This type of adipose tissue enhances metabolism and is thought to provide protective benefits against diabetes and cardiovascular diseases. The researchers utilized infrared thermography to assess the white and brown fat of participants, aiming to establish a correlation between weight fluctuations and the performance of brown fat.

The implications of this study are significant, emphasizing the need for individualized dietary approaches to weight management rather than universal diets that may not suit everyone's unique metabolic responses. As the cycle of weight loss and gain continues to be prevalent among many individuals, this research highlights the importance of understanding how such patterns can impact long-term metabolic health and the effectiveness of weight management strategies.

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