Between 2021 and 2025, more than 2,900 men in Brazil have had their penises amputated as a result of penile cancer, with the disease leading to over 2,300 deaths during this same period, according to the Ministry of Health. Penile cancer is considered a rare type of tumor, largely preventable through basic hygiene practices, HPV vaccination, and surgical procedures such as circumcision, which removes the foreskin and helps reduce the risk of cancer. Doctor Ariê Carneiro, an oncologist from Einstein, emphasizes that penile cancer is entirely avoidable and closely associated with hygiene conditions. He advocates for education on proper hygiene from a young age, teaching boys how to clean themselves and maintain hygiene into adulthood. This proactive approach may significantly reduce incidences of this devastating cancer. The Brazilian Society of Urology (SBU) underscores that maintaining proper hygiene is crucial, particularly for men who retain their foreskin, as urine buildup can lead to irritation and fibrous tissue development, both of which increase cancer risk. Increasing public awareness on these preventive measures is vital for reducing the impact of penile cancer in Brazil, transforming hygiene practices, and potentially saving lives.