Ayuso has raised concerns about the implications of demographic changes in Spain, alleging that the government's recent actions, including nationalizations under the Law of Memory, are aimed at altering voter demographics to threaten her political position. She links these changes to the Great Replacement theory, suggesting a conspiracy where established populations are replaced by immigrant populations, a narrative that has been gaining traction among certain elite circles globally.

The crux of Ayuso's argument focuses on the fear that these demographic shifts will lead to her party's decline in political influence, a fear echoed by some prominent figures who argue that liberal migration policies are intended to shift the political balance toward minority groups. This theory posits that established populations, particularly white and Christian demographics, face existential risks from rising immigrant populations, creating a scenario where they may become marginalized or discriminated against.

In this context, her rhetoric reflects a broader trend in international politics where populist leaders tap into fears of cultural and demographic change to galvanize support. Ayuso's invocation of the Great Replacement theory is designed to rally her base by framing the electoral struggle as a battle for the preservation of their way of life against perceived external threats, thus merging local electoral politics with global conspiratorial narratives around population change and control.