During a family vacation in the Dominican Republic, a seemingly tragic accident occurs when Elena, portrayed by Clara Galle, accidentally runs over a stranger. In a panic and desperate situation, she reaches out to her sisters, Paula (Claudia Salas) and Cris (Paula Usero), who quickly join her in deciding how to handle the fallout of this incident. The stakes are immensely high as Elena faces the possibility of imprisonment, which would leave her very young daughter Ane without a mother. This introduces a gripping moral dilemma about how far they are willing to go to protect each other, a theme that resonates deeply throughout the series.

This eight-part miniseries on Netflix, based on Gillian McAllister's bestselling novel, unpacks the narrative from multiple viewpoints, providing viewers with a multifaceted understanding of the events and emotional repercussions surrounding the fateful night. Each episode provides a different perspective, culminating in a final episode that ties all the strings together, shedding light on the aftermath and the long-term emotional legacy left by such a traumatic event. However, the approach towards depicting the aging of the characters in the final episode has drawn criticism for relying on questionable digital effects, detracting from the powerful narrative at the story's core.

Ultimately, "Quella notte" emerges more as a character-driven exploration of familial bonds and moral choices in the face of crisis, rather than just a simple thriller. The tensions between the sisters, the unfolding drama, and their conflicting responses illuminate deeper themes of sisterhood, loyalty, and the complexities of human emotion as they navigate the harrowing consequences of that night.