The Trump administration is increasing pressure on the Muslim Brotherhood, particularly in relation to the ongoing civil conflict in Sudan, where it is claiming the group has played a substantial role. The U.S. State Department has officially labeled the Sudanese Muslim Brotherhood (SMB) as a 'Designated Global Terrorist,' with plans to designate it as a Foreign Terrorist Organization effective March 16, 2026. This move is a direct response to claims about the SMB having contributed a significant number of fighters to the Sudanese conflict, with alleged support from Iran’s Islamic Revolutionary Guard Corps (IRGC).

The U.S. statement highlights concerns regarding Iranian influence, naming Iran as the 'world’s leading state sponsor of terrorism.' The Trump administration's intention to target both the Iranian regime and the Muslim Brotherhood groups aims to cut off resources that these organizations could potentially use to perpetuate violence and instability. By connecting the SMB’s activities to Iran, the U.S. is framing this designation not only as a counter-terrorism measure but also as part of a broader strategy to counter Iranian influence in the region.

This declaration has significant implications for U.S. foreign policy in the Middle East and Africa. It signals a shift to a more aggressive stance against groups perceived to be affiliated with Iran and highlights the U.S. commitment to combatting terrorism globally. Furthermore, this decision may alter the dynamics of the Sudanese conflict, potentially influencing how regional actors and the international community respond to the ongoing violence and humanitarian crisis in Sudan.