In February 1536, a fleet consisting of fourteen ships arrived at the Riachuelo in the Plata region, bringing between 1,200 and 1,500 people along with horses from Andalusia. The expedition, commanded by Pedro de Mendoza, was marked by its diverse group: nobles, clergymen, soldiers, a physician, and a significant number of women, all aiming to settle the area and trade with local natives for wealth.

From the outset, the expedition faced numerous unexpected challenges. Unlike what was anticipated, the journey did not lead to the discovery of a prosperous city akin to Tenochtitlán, showcasing the harsh realities of early colonial endeavors. The article portrays a vivid glimpse into the historical context of Buenos Aires's foundation and the significant roles played by various individuals, including women.

This narrative emphasizes the importance of women's participation during the early colonial period, which often goes overlooked in historical accounts. As the story unfolds, it sheds light on the complexities and adversities the settlers faced and sets the stage for the future development of Buenos Aires as a significant cultural and economic hub in South America.