University of Lethbridge research could shift how cancer is treated
Researchers at the University of Lethbridge have uncovered a new role for ribonucleic acid in cancer cell energy, which could lead to shifts in cancer treatment methodologies.
At the University of Lethbridge, researchers Trushar Patel and Higor Pereira have made a significant discovery regarding the function of ribonucleic acid (RNA) known as RMRP in cancer growth. During their research, they were able to identify the three-dimensional structure of RMRP for the first time, enabling a deeper understanding of its roles within human cancer cells. This newfound understanding of RNA's architecture may provide critical insights into cancer cell metabolism and growth regulation.
The research highlights how cancer cells require extensive energy to support their rapid growth compared to normal cells, and this energy is primarily derived from mitochondria, often dubbed the powerhouse of the cell. The ability to visualize and understand the structure of RMRP could open new avenues for targeting energy production in cancer treatment, as it plays a key role in managing how energy is utilized within rapidly proliferating tumor cells.
This breakthrough, driven by collaborative efforts between the University of Lethbridge, Ohio State University, and local students, emphasizes the importance of interdisciplinary research in advancing cancer treatment strategies. As researchers continue to explore the implications of RNA in cancer energetics, there may be opportunities to develop targeted therapies that focus on the metabolic demands of cancer cells, potentially shifting the standard approach to cancer care.