Feb 26 • 19:00 UTC 🇪🇸 Spain El País

A living drug eliminates tumors in mice with pancreatic, ovarian, or kidney cancer

A new living drug, a highly sensitive version of the CAR-T therapy, has successfully eliminated tumors in lab mice suffering from pancreatic, ovarian, and kidney cancers.

Recent research has unveiled a groundbreaking living drug that can effectively eradicate tumors in mice with pancreatic, ovarian, and kidney cancers. This innovative therapy is an ultra-sensitive adaptation of the CAR-T treatment, which has already transformed the treatment landscape for blood cancers by achieving complete remissions in cases of leukemia, lymphoma, and myeloma since its experimental inception in 2010. By utilizing genetic engineering, CAR-T therapy enhances the body's defense cells, thereby empowering them to target and destroy cancerous cells more efficiently.

Historically, CAR-T therapies have struggled with solid tumors, which are more common types of cancer compared to blood cancers. The report released today provides a significant breakthrough as study results demonstrate that this newly developed CAR-T variant has successfully removed implanted human tumors from laboratory mice. This finding not only indicates a potential shift in how solid tumors might be treated in the future but also raises hopes for clinical trials involving human patients in the years to come.

The implications of this advancement in cancer treatment are profound, as it could pave the way for more effective therapies against solid tumors, which have often been resistant to previous treatments. If subsequent trials validate these results, this living drug could become a cornerstone of cancer therapy, offering new hope to patients dealing with some of the most challenging forms of cancer.

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