Recent findings have advanced medical knowledge regarding biological differences that affect health issues among genders. These differences impact risk factors, symptoms, and treatment responses, making it imperative to consider gender when diagnosing and treating health conditions. In particular, while coronary artery disease tends to affect women less frequently than men, the implications of this discrepancy in heart attack risk have been previously unclear. Heart disease remains one of the leading causes of death globally for both sexes, with a complex interplay of risk factors that can vary greatly between men and women. Importantly, medical professionals have historically understood that the presence of atherosclerosis doesn't guarantee safety for women, as they can still be vulnerable to heart attacks under certain conditions. This new research seeks to clarify how increased atherosclerotic plaque correlates with heart attack risks in both genders, an area that had received little focused study historically. The outcomes of this research carry significant implications for public health strategies and healthcare delivery focused on gender-based differences in heart disease. Acknowledging these variances in the medical field is essential in developing targeted prevention and treatment plans, ultimately working towards improved health outcomes for women, who traditionally may not have been assessed with the same rigor as men in cardiovascular risk assessments.