The leader of the Jalisco New Generation cartel, Nemesio 'El Mencho' Oseguera, was injured during a shootout with soldiers in the city of Tapalpa, Jalisco state, and he died while being transported to Mexico City. His death triggered a violent backlash, with cartel members nationwide blocking roads and setting vehicles and businesses ablaze. The security situation escalated quickly, resulting in at least 25 members of the National Guard being killed, along with a prison guard, a member of the state prosecutor's office, and 30 suspected cartel members.

The Mexican government had placed a bounty of $15 million on Oseguera's head prior to his death, indicating his significant status within organized crime in Mexico. Following a special forces operation intended to capture him, eight suspected cartel gunmen were killed, and three soldiers were injured, demonstrating the violent confrontation involved. The rapid onset of violence in the aftermath of Oseguera's death underscores the deep instability and ongoing challenges that the Mexican government faces in combating powerful drug cartels.

As violence escalates, fearful residents have sought refuge, highlighting the impact such drug-related conflicts have on ordinary citizens. The government’s battle against organized crime is complicated by the cartel's ability to mobilize and retaliate quickly, as seen in the aftermath of Oseguera's death. This volatile situation not only poses a substantial risk to public safety but also has broader implications for governance, societal stability, and international relations regarding drug trafficking in the region.