The article titled 'This is how you smell the mistake' emphasizes the significance of JavaScript in modern web development. It points out that without enabling JavaScript, users may face issues with the functionality of certain webpages and applications. This can lead to frustrating user experiences, particularly when users are not aware that their browsers require JavaScript to display content properly.

In the context of web browsing, the article highlights common pitfalls faced by users who have disabled or have unsupported JavaScript settings. It underlines how modern websites utilize JavaScript for interactive features, dynamic content updates, and improved user engagement. Not using JavaScript can hinder accessibility to a wealth of information and services available online, as many sites may not function correctly.

Furthermore, the article touches upon the broader implications of a lack of JavaScript compatibility, including potential accessibility issues for users who may be unaware of their browser settings. It suggests that developers and users alike need to be mindful of these issues to ensure a smoother web experience, thus reinforcing the argument for always enabling JavaScript in browsers for enhanced functionality and usability.