In 2025, the Prairie Harm Reduction (PHR) in Saskatoon reported a staggering increase in the number of overdoses treated, tripling the figures compared to the previous year. The site has managed to support a 22 percent rise in individuals, emphasizing its critical role in tackling the ongoing toxic drug crisis in the city. Over 150 overdose interventions were successfully performed, showcasing the dire need for these services as the overdose epidemic continues to escalate.

The PHR's executive director, Kayla Demong, underscored the significance of their interventions in maintaining community safety. The statistics from the site correlate with alarming observations made by local authorities. For instance, Saskatoon Fire Deputy Chief Rob Hogan noted a drastic increase in reported overdoses, seeing over 2,100 cases in just the current year, nearly double the figures from 2024. Such increases call for urgent community awareness and policy interventions to address these public health concerns.

Both PHR's staff and first responders have attributed the rise in overdose reversals to the effectiveness of naloxone, a medication designed to counteract opioid overdoses. However, the issuance of toxic drug alerts in the city indicates a persisting threat from dangerous substances, including a veterinarian sedative that has recently made its way into the local drug supply. This situation underscores the need for enhanced preventive measures and resources to combat the growing drug crisis in Saskatoon and beyond.