LARGE-PD, which stands for the Latin American Consortium for Research on Genetics of Parkinson's Disease, was established in 2005 as a multicenter collaboration across Latin America to enhance understanding of Parkinson's disease in the region. The initiative aims to provide insights into the prevalence, causes, and potential treatments for Parkinson's, which currently ranks as the second most common neurodegenerative disorder following Alzheimer's. Symptoms can range from motor functions like tremors to non-motor symptoms, complicating diagnosis and treatment.