Feb 7 • 21:03 UTC 🇪🇸 Spain elDiario.es

The 'Celtic gene' of hemochromatosis in Asturias: when the blood is safe but cannot be donated

Asturias faces a blood donor crisis as many individuals, despite having safe blood, are unable to donate due to hereditary hemochromatosis linked to the 'Celtic gene'.

Asturias is experiencing a significant blood donation crisis, as many eligible donors are barred from giving blood due to hereditary hemochromatosis, a genetic disorder commonly associated with the 'Celtic gene'. This condition affects a notable portion of the population in the region, leading to a discrepancy in donor eligibility that varies across different Spanish communities. While their blood is deemed safe, the regulations in Asturias prevent these individuals from participating in donation drives.

Hemochromatosis is primarily caused by the C282Y mutation, which results in excessive iron absorption in the intestines. As iron accumulates in vital organs such as the liver, pancreas, and heart, it can cause significant health issues through toxicity. Although the prevalence of this mutation is not extremely high nationwide, it is relatively common in northern Spain, particularly in Asturias, where many residents find themselves unable to donate blood due to the genetic condition. This situation has raised concerns among health officials as they struggle to meet the community's blood needs.

The predicament highlights a larger conversation about blood donation policies and genetic conditions, questioning the fairness of varying rules across regions. Individuals who might otherwise be able to donate blood in other parts of Spain are unable to do so in Asturias, reinforcing the idea that while their blood is safe, the existing regulations are restrictive and may need to be reevaluated to accommodate genetic realities. Addressing this issue could open pathways for these individuals to contribute to blood donation efforts.

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