The 'Sanctuary of Dona Romana', officially known as the Centro Bom Jesus de Nazaré, is a mystical and sacred site located in Natividade, Tocantins, Brazil. It draws people from all over the country who seek its spiritual healing and guidance, highlighting its importance as a refuge during times of turmoil. The sanctuary is led by Dona Romana, an 85-year-old spiritual guide, known for her herbal remedies and profound wisdom, making her a pivotal figure in the community and beyond.

Dona Romana has inspired various cultural representations, including the character Mercedes from the soap opera 'O Outro Lado do Paraíso', played by actress Fernanda Montenegro. Her life story, rich in tradition and spirituality, has also been documented in films and other media, contributing to the growing interest in her sanctuary. This suggests that her influence transcends the local, connecting spiritual and emotional needs with popular culture and media.

As the guardian of the sanctuary, Dona Romana emphasizes the site's role as a spiritual anchor for the Earth, suggesting a broader cosmic significance attributed to their faith. The sanctuary serves not only as a place for personal healing but also as a cultural landmark, where spirituality, community advice, and traditional medicine intersect, reflecting the rich tapestry of Brazilian spirituality and community life.